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著者: Marina de Tommaso, Nicola Specchio, Vittorio Sciruicchio, Olimpia Difruscolo, Luigi Maria Specchio
雑誌名: Mov Disord. 2004 Dec;19(12):1516-8. doi: 10.1002/mds.20235.
Abstract/Text
To evaluate the efficacy of rivastigmine on motor and cognitive impairment in Huntington's disease (HD), we carried out a prospective, open-label, randomized, controlled study. Twenty-one HD patients were enrolled: 14 were randomly sorted into medication and 7 to no-treatment groups. Clinical and demographic features were similar between groups. After 8 months, an efficacy evaluation was carried out to compare the two groups. The improvement of cholinergic transmission in HD patients seemed to have a slight effect in ameliorating cognitive performance and slowing motor deterioration.
2004 Movement Disorder Society.
PMID 15390067 Mov Disord. 2004 Dec;19(12):1516-8. doi: 10.1002/mds.20235.
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