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著者: Fabrice Ivanes, Jean Dewaele, Caroline Touboul, Philippe Gatault, Bénédicte Sautenet, Christelle Barbet, Matthias Büchler, Laurent Quilliet, Denis Angoulvant, Jean-Michel Halimi
雑誌名: BMC Nephrol. 2020 Jul 14;21(1):273. doi: 10.1186/s12882-020-01929-z. Epub 2020 Jul 14.
Abstract/Text
BACKGROUND: Renal infarction (RI) is a rare disease with poor prognosis. Appropriate secondary prevention treatment is essential and requires an exhaustive etiological assessment. We aimed to determine whether invasive endovascular explorations may improve the diagnostic process and change the secondary prevention treatment strategy in RI patients.
METHODS: We report a retrospective observational study of 25 RI patients referred to Tours University Hospital between 2011 and 2018 for etiological investigation including renal arteriography and intravascular ultrasonography (IVUS). We sought for antithrombotic treatment regimen, vital status, bleeding and ischemic outcomes during the median follow-up of 59 months.
RESULTS: Invasive explorations showed local arterial disease in 14 patients (56%). This led to a diagnosis or change in diagnosis in 9 patients (36%) and to a change in antithrombotic strategy in 56% of cases, with an increased prescription of antiplatelet therapy. No patient died, only two patients (8%) had persistent mild renal insufficiency. One IVUS complication was reported and treated without any significant long-term consequences.
CONCLUSION: Invasive endovascular investigations of RI may modify the secondary prevention treatment through a better assessment of the aetiology of RI. Multicentric randomized studies are necessary to advocate the hypothesis that invasive exploration of renal artery can improve long-term prognosis.
PMID 32664890 BMC Nephrol. 2020 Jul 14;21(1):273. doi: 10.1186/s12882-020-01929-z. Epub 2020 Jul 14.
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