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著者: Arnaud Delezire, Marianne Terrasse, Julien Bouet, Maxence Laot, Vanessa Brun, Emmanuel Oger, Cécile Vigneau
雑誌名: J Nephrol. 2021 Oct;34(5):1501-1509. doi: 10.1007/s40620-020-00953-4. Epub 2021 Mar 25.
Abstract/Text
INTRODUCTION: Acute renal infarction is a rare occurence, whose prognosis and long-term outcomes remain poorly studied. This study evaluated whether clinical and radiological features at diagnosis can be associated with the long-term outcomes (blood pressure, kidney function and mortality).
METHODS: We retrospectively analyzed the demographic, clinical, biological and radiological data of patients with acute renal infarction hospitalized at Rennes University Hospital between 1997 and 2017 (n = 94).
RESULTS: Patients were followed-up for a median of 60 months. At time of diagnosis of acute renal infarction median age was 53 years, 45% of the patients had acute hypertension, and 31% had Acute Kidney Injury (AKI) requiring dialysis in seven patients. The median Lactate DeHydrogenase (LDH) level was 977 IU/mL. The median extent of kidney damage was 14%, with left renal involvement in 51% of patients. At 60 months of follow-up, 66% of patients had developed Chronic Kidney Disease (CKD) stage 3 or higher, and 55% had hypertension since diagnosis. Age, acute development of hypertension and AKI at diagnosis were associated with long-term CKD (stage 3 or higher) in multivariate analyses, but the extent of kidney damage was not. During the follow-up, 21% of patients died, and only age resulted as a predisposing factor. No tested factor was correlated with long-term hypertension.
DISCUSSION: Age, acute development of hypertension, and AKI were correlated with long term CKD, whereas no factor was correlated with long-term hypertension after acute renal infarction.
© 2021. Italian Society of Nephrology.
PMID 33765299 J Nephrol. 2021 Oct;34(5):1501-1509. doi: 10.1007/s40620-020-00953-4. Epub 2021 Mar 25.
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