| |
著者: Lynn Petukhova, Madeleine Duvic, Maria Hordinsky, David Norris, Vera Price, Yutaka Shimomura, Hyunmi Kim, Pallavi Singh, Annette Lee, Wei V Chen, Katja C Meyer, Ralf Paus, Colin A B Jahoda, Christopher I Amos, Peter K Gregersen, Angela M Christiano
雑誌名: Nature. 2010 Jul 1;466(7302):113-7. doi: 10.1038/nature09114.
Abstract/Text
Alopecia areata (AA) is among the most highly prevalent human autoimmune diseases, leading to disfiguring hair loss due to the collapse of immune privilege of the hair follicle and subsequent autoimmune attack. The genetic basis of AA is largely unknown. We undertook a genome-wide association study (GWAS) in a sample of 1,054 cases and 3,278 controls and identified 139 single nucleotide polymorphisms that are significantly associated with AA (P
PMID 20596022 Nature. 2010 Jul 1;466(7302):113-7. doi: 10.1038/nature09114.
|
