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img  3:  Burning mouth syndrome: a retrospective study investigating spontaneous remission and response to treatments.
 
著者: A Sardella, G Lodi, F Demarosi, C Bez, S Cassano, A Carrassi
雑誌名: Oral Dis. 2006 Mar;12(2):152-5. doi: 10.1111/j.1601-0825.2005.01174.x.
Abstract/Text OBJECTIVE: The aim of this investigation was to evaluate the spontaneous remission rate of burning mouth syndrome (BMS) in a group of subjects suffering from this syndrome.
SUBJECTS AND METHODS: The medical records of BMS patients attending the Unit of Oral Medicine (1995-2002) were reviewed. The patients with a follow-up period of at least 18 months were then contacted over phone and interviewed using a structured ad hoc questionnaire to record their current symptoms and data about their treatment responses to the therapies.
RESULTS: Forty-eight women and five men with a mean age of 67.7 years (range 33-82 years) were included in the study (mean duration of BMS 5.5 years, s.d. +/-1.9 years, mean follow-up period of 56 months). As a consequence of different treatments, 26 patients (49.0%) reported no change in oral symptoms, 15 (28.3%) moderate improvement and 10 (18.9%) a worsening of oral complaints. Only two patients (3.7%) reported a complete spontaneous remission of oral symptoms without any treatment.
CONCLUSIONS: In this study, a complete spontaneous remission was observed in 3% of the patients within 5 years after the onset of BMS. A moderate improvement was obtained in <30% of the subjects.

PMID 16476036  Oral Dis. 2006 Mar;12(2):152-5. doi: 10.1111/j.1601-0825.2005.01174.x.
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