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著者: Shigeki Nakamura, Katsunori Yanagihara, Yukihiro Kaneko, Hideaki Ohno, Yasuhito Higashiyama, Yoshitsugu Miyazaki, Youichi Hirakata, Kszunori Tomono, Takayoshi Tashiro, Shigeru Kohno
雑誌名: Kansenshogaku Zasshi. 2004 May;78(5):446-50.
Abstract/Text
A 53-year-old male was admitted to our hospital with a high fever and pain in the right arm. He was diagnosed as toxic shock-like syndrome by Streptococcus pyogenes. His arm was amputated because of necrotizing myositis and his renal damage was severe, he was treated in the intensive care unit with continuous hemodiafiltration. Bacteria were isolated from blood, ascites, pleural effusion, skin, and muscle. He was treated with a large amount of ampicillin, clindamycin, and gammaglobulin. However, his general status became worse. His illness improved after linezolid was administered. The reason for the success in treatment with linezolid, which was the inhibitory effect on bacterial toxin and its excellent penetration into the tissue.
PMID 15211868 Kansenshogaku Zasshi. 2004 May;78(5):446-50.
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