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関連論文:
img  4:  Effect of maternal age on blood loss during parturition: a retrospective multivariate analysis of 10,053 cases.
 
著者: Akihide Ohkuchi, Tamaho Onagawa, Rie Usui, Toshimitsu Koike, Mitsuhiro Hiratsuka, Akio Izumi, Takashi Ohkusa, Shigeki Matsubara, Ikuo Sato, Mitsuaki Suzuki, Hisanori Minakami
雑誌名: J Perinat Med. 2003;31(3):209-15. doi: 10.1515/JPM.2003.028.
Abstract/Text OBJECTIVE: An extensive study as to whether maternal age itself is a risk factor for blood loss during parturition.
METHOD: A total of 10,053 consecutive women who delivered a singleton infant were studied. The excess blood loss was defined separately for women with vaginal and cesarean deliveries as > or = 90th centile value for each delivery mode. The effects of 13 potential risk factors on blood loss were analyzed using multivariate analysis.
RESULTS: The 90th centile value of blood loss was 615 ml and 1,531 ml for women with vaginal and cesarean deliveries, respectively. A low lying placenta (odds ratio [OR], 4.4), previous cesarean (3.1), operative delivery (2.6), leiomyoma (1.9), primiparity (1.6), and maternal age > or = 35 years (1.5) were significant independent risk factors for excess blood loss in women with vaginal delivery. Placenta previa (6.3), leiomyoma (3.6), low lying placenta (3.3), and maternal age > or = 35 years (1.8) were significant independent risk factors for excess blood loss in women with cesarean sections.
CONCLUSION: A maternal age of > or = 35 years was an independent risk factor for excess blood loss irrespective of the mode of delivery, even after adjusting for age-related complications such as leiomyoma, placenta previa, and low lying placenta.

PMID 12825476  J Perinat Med. 2003;31(3):209-15. doi: 10.1515/JPM.2003.028.
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