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関連論文:
img  4:  Efficacy of mastoidectomy on MRSA-infected chronic otitis media with tympanic membrane perforation.
 
著者: Toshihiko Mutoh, Osamu Adachi, Kojiro Tsuji, Mieko Okunaka, Masafumi Sakagami
雑誌名: Auris Nasus Larynx. 2007 Mar;34(1):9-13. doi: 10.1016/j.anl.2006.05.017. Epub 2006 Aug 21.
Abstract/Text OBJECTIVES: To retrospectively evaluate the efficacy of mastoidectomy on methicillin-resistant Staphylococcus aureus (MRSA)-infected chronic otitis media in comparison with methicillin-susceptible Staphylococcus aureus (MSSA)-infected otitis media.
METHODS: Between January 1998 and October 2003, 18 ears underwent surgery for MRSA-infected chronic otitis media with tympanic membrane perforation at the Department of Otolaryngology, Hyogo College of Medicine. Another 33 ears underwent surgery for MSSA-infected chronic otitis media with tympanic membrane perforation during the same period. The postoperative results of graft success rate, hearing results and other complications were compared between MRSA-infected and MSSA-infected ears with or without mastoidectomy, and discharging or dry ears.
RESULTS: In MRSA, the mastoidectomy group tended to have a better graft success rate than the non-mastoidectomy group. In MSSA, there were almost the same graft success rate and hearing results between the mastoidectomy and non-mastoidectomy groups regardless of the presence of discharge. In MRSA-infected discharging ears, the rate of postoperative complications (ear drum perforation, persistent otorrhea, and dehiscence of skin incision) were significantly lower in the mastoidectomy group than in the non-mastoidectomy group (p=0.046).
CONCLUSION: Mastoidectomy had significantly better results concerning postoperative complications in discharging ears with MRSA-infected chronic otitis media. We recommend performing tympanoplasty with mastoidectomy in MRSA-infected chronic otitis media.

PMID 16920308  Auris Nasus Larynx. 2007 Mar;34(1):9-13. doi: 10.1016/j.anl.2006.05.017. Epub 2006 Aug 21.
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