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著者: Basem M Alraddadi, John T Watson, Abdulatif Almarashi, Glen R Abedi, Amal Turkistani, Musallam Sadran, Abeer Housa, Mohammad A Almazroa, Naif Alraihan, Ayman Banjar, Eman Albalawi, Hanan Alhindi, Abdul Jamil Choudhry, Jonathan G Meiman, Magdalena Paczkowski, Aaron Curns, Anthony Mounts, Daniel R Feikin, Nina Marano, David L Swerdlow, Susan I Gerber, Rana Hajjeh, Tariq A Madani
雑誌名: Emerg Infect Dis. 2016 Jan;22(1):49-55. doi: 10.3201/eid2201.151340.
Abstract/Text
Risk factors for primary Middle East respiratory syndrome coronavirus (MERS-CoV) illness in humans are incompletely understood. We identified all primary MERS-CoV cases reported in Saudi Arabia during March-November 2014 by excluding those with history of exposure to other cases of MERS-CoV or acute respiratory illness of unknown cause or exposure to healthcare settings within 14 days before illness onset. Using a case-control design, we assessed differences in underlying medical conditions and environmental exposures among primary case-patients and 2-4 controls matched by age, sex, and neighborhood. Using multivariable analysis, we found that direct exposure to dromedary camels during the 2 weeks before illness onset, as well as diabetes mellitus, heart disease, and smoking, were each independently associated with MERS-CoV illness. Further investigation is needed to better understand animal-to-human transmission of MERS-CoV.
PMID 26692185 Emerg Infect Dis. 2016 Jan;22(1):49-55. doi: 10.3201/eid2201.151340.
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