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蛋白漏出性胃腸症

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		27:	[Protein-losing enteropathy].
			著者: A Amiot 雑誌名: Rev Med Interne. 2015 Jul;36(7):467-73. doi: 10.1016/j.revmed.2014.12.001. Epub 2015 Jan 21. Abstract/Text Protein-losing enteropathy is a rare syndrome of gastrointestinal protein loss. The primary causes can be classified into lymphatic leakage due to increased interstitial pressure and increased leakage of protein-rich fluids due to erosive or non-erosive gastrointestinal disorders. The diagnosis of protein-losing enteropathy should be considered in patients with chronic diarrhea and peripheral oedema. The diagnosis of protein-losing enteropathy is most commonly based on the determination of fecal alpha-1 antitrypsin clearance. Most protein-losing enteropathy cases are the result of either lymphatic obstruction or a variety of gastrointestinal disorders and cardiac diseases, while primary intestinal lymphangiectasia (Waldmann's disease) is less common. Treatment of protein-losing enteropathy targets the underlying disease but also includes dietary modification, such as high-protein and low-fat diet along with medium-chain triglyceride supplementation. Copyright © 2014 Société nationale française de médecine interne (SNFMI). Published by Elsevier SAS. All rights reserved. PMID 25618488 Rev Med Interne. 2015 Jul;36(7):467-73. doi: 10.1016/j.revmed.2014.12.001. Epub 2015 Jan 21.