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著者: Yutaka Suzuki, Yutaka Atomi, Masanori Sugiyama, Shuji Isaji, Kazuo Inui, Wataru Kimura, Makoto Sunamura, Toru Furukawa, Akio Yanagisawa, Jo Ariyama, Tadahiro Takada, Hidenobu Watanabe, Koichi Suda, Japanese multiinstitutional study of intraductal papillary mucinous tumor and mucinous cystic tumor
雑誌名: Pancreas. 2004 Apr;28(3):241-6.
Abstract/Text
The Japan Pancreas Society performed a multiinstitutional, retrospective study of 1379 cases of intraductal papillary mucinous tumor (IPMT) and 179 cases of mucinous cystic tumor (MCT) of the pancreas. Clinicopathologic features and postoperative long-term outcomes were investigated. IPMT were most frequently found in men and in the head of the pancreas. In contrast, all patients with MCT were women. Ovarian-type stroma were found in only 42.2% of the MCT cases. Prognostic indicators of malignant IPMT included advanced age, positive symptoms, abundant mucous secretion, presence of large nodules and/or large cysts, remarkable dilatation of the main pancreatic duct, and main duct- or combined-type IPMT. Advanced age, positive symptoms, and presence of large nodules and/or large cysts were predictive of malignant MCT. The 5-year survival rate of IPMT patients was 98%-100% in adenoma to noninvasive carcinoma cases, 89% in minimally invasive carcinoma cases, and 57.7% in invasive carcinoma cases. The 5-year survival rate of MCT patients was 100% in adenoma to minimally invasive carcinoma cases and 37.5% in invasive carcinoma cases. In conclusion, IPMT and MCT show distinct clinicopathologic and prognostic differences. The results from this study may contribute to the diagnosis and treatment of IPMT and MCT.
PMID 15084964 Pancreas. 2004 Apr;28(3):241-6.
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