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著者: S P Y Wong, C M Chu, C H Kan, H S Tsui, W L Ng
雑誌名: J Clin Rheumatol. 2009 Dec;15(8):389-92. doi: 10.1097/RHU.0b013e3181c3f87e.
Abstract/Text
Drug-induced acute pneumonitis is a rare but potentially fatal adverse drug reaction. A high index of suspicion is needed for early diagnosis as it mimics community acquired pneumonia and interstitial lung disease that can occur in rheumatoid arthritis. We report a 32-year-old Chinese lady who suffered from leflunomide-induced pneumonitis and improved dramatically after receiving cholestyramine wash-out therapy. This case illustrates the need for clinical alertness to this potentially fatal complication. When in doubt, discontinuation of leflunomide and empirical wash-out therapy should be administered without delay.
PMID 19955995 J Clin Rheumatol. 2009 Dec;15(8):389-92. doi: 10.1097/RHU.0b013e3181c3f87e.
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