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著者: O Salomon, R Huna-Baron, D M Steinberg, S Kurtz, U Seligsohn
雑誌名: Eye (Lond). 1999 Jun;13 ( Pt 3a):357-9. doi: 10.1038/eye.1999.90.
Abstract/Text
PURPOSE: To retrospectively evaluate in patients with non-arteritic ischaemic optic neuropathy (NAION) whether aspirin reduces the frequency of second eye involvement.
METHODS: In 52 patients who presented with NAION between 1984 and 1997 adequate information was available regarding use of aspirin, presence of risk factors and second eye involvement.
RESULTS: Second eye involvement was noted in 8 of 16 patients (50%) who did not receive aspirin, in 3 of 8 patients (38%) who received 100 mg/day aspirin and in only 5 of 28 patients (18%) who received aspirin 325 mg/day. Moreover, mean time to second eye involvement was 63 months in patients who did not receive aspirin versus 156 months in patients who received aspirin 325 mg/day.
CONCLUSION: Our results strongly suggest that aspirin at 325 mg/day may be effective in reducing the frequency of second eye involvement with NAION.
PMID 10624433 Eye (Lond). 1999 Jun;13 ( Pt 3a):357-9. doi: 10.1038/eye.1999.90.
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