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img  6:  Blepharospasm in Japan: A Clinical Observational Study From a Large Referral Hospital in Tokyo.
 
著者: M Wakakura, A Yamagami, M Iwasa
雑誌名: Neuroophthalmology. 2018 Oct;42(5):275-283. doi: 10.1080/01658107.2017.1409770. Epub 2018 Jan 9.
Abstract/Text Focal dystonia is regarded as a characteristic feature of blepharospasm. However, patients do not always present with motor symptoms. To clarify the clinical features of blepharospasm in Japan, we conducted a retrospective observational study involving a large population of patients from a single institution. Common symptoms included difficulty opening the eyes, photophobia, and ocular pain/irritation. Initial symptoms often occurred following the long-term use of psychotropics such as etizoram, benzodiazepines, and zolpidem (32% of patients). Our findings demonstrated that the clinical presentation of blepharospasm is heterogenous, and that understanding regarding sensory-dominant forms of the disease may be poor among practitioners in Japan.

PMID 30258472  Neuroophthalmology. 2018 Oct;42(5):275-283. doi: 10.1080/01658107.2017.1409770. Epub 2018 Jan 9.
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