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著者: Mikie Yamamoto, Kenji Wada-Isoe, Makoto Yoneda, Koji Doi, Hisanori Kowa, Kenji Nakashima
雑誌名: Rinsho Shinkeigaku. 2010 Aug;50(8):581-4.
Abstract/Text
We reported a 61-year-old man who had developed acute cerebellar ataxia in the trunk and the lower limbs. His chemical blood analysis showed very mild hypothyroidism and the presence of serum anti-thyroid peroxidase (TPO) antibody and anti-NH2 terminal of alpha-enolase (NAE) antibody. While cerebellar atrophy was not evident on magnetic resonance imaging (MRI) of the brain, 99mTc-ECD SPECT using the easy Z-score imaging system (eZIS) showed decreased regional cerebral blood flow (rCBF) in the vermis of cerebellum. His cerebellar ataxia improved spontaneously within three weeks. The present case is very rare and suggests that anti-NAE autoantibody may be associated with actue cerebellar ataxia.
PMID 20803969 Rinsho Shinkeigaku. 2010 Aug;50(8):581-4.
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