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著者: Yasunari Otawara, Kuniaki Ogasawara, Akira Ogawa, Keiko Yamadate
雑誌名: Stroke. 2005 Jan;36(1):142-3. doi: 10.1161/01.STR.0000149925.36914.4e. Epub 2004 Nov 29.
Abstract/Text
BACKGROUND AND PURPOSE: This prospective study investigated whether surgery for unruptured intracranial aneurysms (UIAs) affects cognitive function and cerebral blood flow (CBF).
METHODS: Cognitive tests using the Wechsler Adult Intelligence Scale-Revised, Wechsler Memory Scale, Rey-Osterrieth Complex Figure test, and CBF measurements using single-photon emission computed tomography were performed before and after surgery for UIAs in 44 patients < or =70 years of age.
RESULTS: Group-rate analysis showed the verbal intelligence quotient (IQ), performance IQ, full-scale IQ, and recall trial scores of the Rey-Osterrieth Complex Figure test all increased significantly after surgery, whereas the Wechsler Memory Scale and copy trial scores of the Rey-Osterrieth Complex Figure test were not significantly different. Event-rate analysis demonstrated that no patient showed impaired cognition. There was no significant difference between CBF before and after surgery.
CONCLUSIONS: Surgical repair for UIAs does not impair cognition or CBF in patients without postoperative restrictions in lifestyle.
PMID 15569864 Stroke. 2005 Jan;36(1):142-3. doi: 10.1161/01.STR.0000149925.36914.4e. Epub 2004 Nov 29.
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