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著者: Christina Gerth, Giuseppe Mirabella, Xiaoqing Li, Thomas Wright, Carol Westall, Linda Colpa, Agnes M F Wong
雑誌名: Invest Ophthalmol Vis Sci. 2008 Aug;49(8):3432-7. doi: 10.1167/iovs.08-1836. Epub 2008 Apr 25.
Abstract/Text
PURPOSE: Infantile esotropia is associated with maldevelopment of cortical visual motion processing, manifested as directional asymmetry of motion visual evoked potentials (mVEPs). The purpose of this study was to determine whether early surgery at or before age 11 months could promote the development of cortical visual motion processing in human infants, compared with standard surgery at age 11 to 18 months.
METHODS: Sixteen children with a constant, infantile esotropia >or=30 prism diopters and onset before age 6 months were recruited prospectively. Eight of them underwent early surgery at RESULTS: The mean asymmetry index and interocular phase difference in the early surgery group were comparable to that in age-matched control subjects, and they were significantly lower than those in the standard surgery group.
CONCLUSIONS: Early surgery for infantile esotropia promotes the development of cortical visual motion processing, whereas standard surgery is associated with abnormal mVEPs. The results provide additional evidence that early strabismus repair is beneficial for cortical development in human infants.
PMID 18441299 Invest Ophthalmol Vis Sci. 2008 Aug;49(8):3432-7. doi: 10.1167/iovs.08-1836. Epub 2008 Apr 25.
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