浮腫の病態生理
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浮腫を形成する要因には間質および血管内の静水圧と膠質浸透圧が主に関与している。さらに炎症ではサイトカインの放出により、毛細血管の透過性が亢進する。また、リンパ管の閉塞によりリンパ浮腫が起こる。
出典
1:
Peripheral edema.
著者:
Shaun Cho, J Edwin Atwood
雑誌名:
Am J Med. 2002 Nov;113(7):580-6.
Abstract/Text
Peripheral edema often poses a dilemma for the clinician because it is a nonspecific finding common to a host of diseases ranging from the benign to the potentially life threatening. A rational and systematic approach to the patient with edema allows for prompt and cost-effective diagnosis and treatment. This article reviews the pathophysiologic basis of edema formation as a foundation for understanding the mechanisms of edema formation in specific disease states, as well as the implications for treatment. Specific etiologies are reviewed to compare the diseases that manifest this common physical sign. Finally, we review the clinical approach to diagnosis and treatment strategies.
Am J Med. 2002 Nov;113(7):580-6.