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S状結腸軸捻転治療アルゴリズム

出典
imgimg
1: Volvulus of the sigmoid colon.
著者: Raveenthiran V, Madiba TE, Atamanalp SS, De U.
雑誌名: Colorectal Dis. 2010 Jul;12(7 Online):e1-17. doi: 10.1111/j.1463-1318.2010.02262.x. Epub 2010 Mar 10.
Abstract/Text: AIMS: The current status of sigmoid volvulus (SV) was reviewed to assess trends in management and to assess the literature.
METHOD: The literature on SV was retrieved using PubMed, Embase, Scopus, Pakmedinet, African Journals online (AJOL), Indmed and Google scholar. These databases were searched for text words including 'sigmoid', 'colon' and 'volvulus'. Relevant nonindexed surgical journals published from endemic countries were also manually searched. We focused on original articles published within the last 10 years; but classical references prior to this period were also included. Seminal papers published in non-English languages were also included.
RESULTS: Sigmoid volvulus is a leading cause of acute colonic obstruction in South America, Africa, Eastern Europe and Asia. It is rare in developed countries such as USA, UK, Japan and Australia. Characteristic geographic variations in the incidence, clinical features, prognosis and comorbidity of SV justify recognition of endemic and sporadic subtypes. Controversy on aetiologic agents can be minimized by classifying them into 'predisposing' and 'precipitating' factors. Modern imaging systems, although more effective than plain radiographs, are yet to gain popularity. Emergency endoscopic reduction is the treatment of choice in uncomplicated patients. But it is only a temporizing procedure, and it should be followed in most cases by elective definitive surgery. Resection of the redundant sigmoid colon is the gold standard operation. The role of newer nonresective alternatives is yet to be ascertained. Although emergency resection with primary anastomosis (ERPA) has been controversial in the past, it is now increasingly accepted as a safe option with superior results. Management in elderly debilitated patients is extremely difficult. Paediatric SV significantly differs from that in adults. SV is frequently associated with neuropsychiatric diseases, diabetes mellitus and Chagas disease. The overall mortality in recent studies is < 5%.
CONCLUSION: There are almost no randomised controlled studies. According to the grading system of Oxford Center for Evidence Based Medicine (CEVM), available published evidence is at level 4. The recommendations resulting form this review are of 'C' grade.
Colorectal Dis. 2010 Jul;12(7 Online):e1-17. doi: 10.1111/j.1463-1318....

腸重積の腹部CT(target pattern)

内部に低吸収域と高吸収域が混在する同心円状の層状構造を持つ腫瘤陰影を認める。重積を横断面像として捉えるとtarget patternとして描出される。
出典
imgimg
1: Intussusception in adults: what radiologists should know.
著者: Baleato-González S, Vilanova JC, García-Figueiras R, Juez IB, Martínez de Alegría A.
雑誌名: Emerg Radiol. 2012 Apr;19(2):89-101. doi: 10.1007/s10140-011-1006-z. Epub 2011 Dec 27.
Abstract/Text: Adult intussusception (AI) is a rare entity with an organic lesion within the intussusception in 70-90% of the cases. Intussusception is classified according to location, etiology, and to the presence or not of a lead point. We illustrate several causes of AI with a variety of radiological findings on plain film, ultrasonography, computed tomography, magnetic resonance, and endoscopy seen at our institution. Imaging plays a major role in their diagnosis and in determining the appropriate treatment.
Emerg Radiol. 2012 Apr;19(2):89-101. doi: 10.1007/s10140-011-1006-z. E...

腸重積の腹部CT(sausage-shaped pattern)

重積を縦断面像として捉えるとsausage-shaped patternとして描出される。
出典
imgimg
1: Intussusception in adults: what radiologists should know.
著者: Baleato-González S, Vilanova JC, García-Figueiras R, Juez IB, Martínez de Alegría A.
雑誌名: Emerg Radiol. 2012 Apr;19(2):89-101. doi: 10.1007/s10140-011-1006-z. Epub 2011 Dec 27.
Abstract/Text: Adult intussusception (AI) is a rare entity with an organic lesion within the intussusception in 70-90% of the cases. Intussusception is classified according to location, etiology, and to the presence or not of a lead point. We illustrate several causes of AI with a variety of radiological findings on plain film, ultrasonography, computed tomography, magnetic resonance, and endoscopy seen at our institution. Imaging plays a major role in their diagnosis and in determining the appropriate treatment.
Emerg Radiol. 2012 Apr;19(2):89-101. doi: 10.1007/s10140-011-1006-z. E...

腸重積の腹部CT(reniform pattern)

浮腫により腸管壁が肥厚している。血行障害を示唆する所見である。
出典
imgimg
1: Intussusception in adults: what radiologists should know.
著者: Baleato-González S, Vilanova JC, García-Figueiras R, Juez IB, Martínez de Alegría A.
雑誌名: Emerg Radiol. 2012 Apr;19(2):89-101. doi: 10.1007/s10140-011-1006-z. Epub 2011 Dec 27.
Abstract/Text: Adult intussusception (AI) is a rare entity with an organic lesion within the intussusception in 70-90% of the cases. Intussusception is classified according to location, etiology, and to the presence or not of a lead point. We illustrate several causes of AI with a variety of radiological findings on plain film, ultrasonography, computed tomography, magnetic resonance, and endoscopy seen at our institution. Imaging plays a major role in their diagnosis and in determining the appropriate treatment.
Emerg Radiol. 2012 Apr;19(2):89-101. doi: 10.1007/s10140-011-1006-z. E...

腸重積症が診断された成人患者の臨床的特徴

出典
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1: Adult intussusception: presentation, management, and outcomes of 148 patients.
著者: Lindor RA, Bellolio MF, Sadosty AT, Earnest F 4th, Cabrera D.
雑誌名: J Emerg Med. 2012 Jul;43(1):1-6. doi: 10.1016/j.jemermed.2011.05.098. Epub 2012 Jan 12.
Abstract/Text: BACKGROUND: Intussusception is a predominantly pediatric diagnosis that is not well characterized among adults. Undiagnosed cases can result in significant morbidity, making early recognition important for clinicians.
STUDY OBJECTIVES: We describe the presentation, clinical management, disposition, and outcome of adult patients diagnosed with intussusception during a 13-year period.
METHODS: A retrospective study of consecutive adult patients diagnosed with intussusception at a tertiary academic center was carried out from 1996 to 2008. Cases were identified using International Classification of Diseases, 9(th) Revision codes and a document search engine. Data were abstracted in duplicate by two independent authors.
RESULTS: Among 148 patients included in the study, the most common symptoms at presentation were abdominal pain (72%), nausea (49%), and vomiting (36%). Twenty percent were asymptomatic. Sixty percent of cases had an identifiable lead point. Patients presenting to the emergency department (ED) (31%) had higher rates of abdominal pain (relative risk [RR] 5.7) and vomiting (RR 3.4), and were more likely to undergo surgical intervention (RR 1.8) than patients diagnosed elsewhere. There were 77 patients who underwent surgery within 1 month; patients presenting with abdominal pain (RR 2.2), nausea (RR 1.7), vomiting (RR 1.4), and bloody stool (RR 1.9) were more likely to undergo surgery.
CONCLUSIONS: Adult intussusception commonly presents with abdominal pain, nausea, and vomiting; however, approximately 20% of cases are asymptomatic and seem to be diagnosed by incidental radiologic findings. Patients presenting to an ED with intussusception due to a mass as a lead point or in an ileocolonic location are likely to undergo surgical intervention.

Copyright © 2012 Elsevier Inc. All rights reserved.
J Emerg Med. 2012 Jul;43(1):1-6. doi: 10.1016/j.jemermed.2011.05.098. ...

成人腸重積症の病因

出典
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1: Adult intussusception in the last 25 years of modern imaging: is surgery still indicated?
著者: Onkendi EO, Grotz TE, Murray JA, Donohue JH.
雑誌名: J Gastrointest Surg. 2011 Oct;15(10):1699-705. doi: 10.1007/s11605-011-1609-4. Epub 2011 Jul 6.
Abstract/Text: BACKGROUND: Because most adult intussusceptions are reportedly due to malignancy, operative treatment is recommended. With current availability of computed tomography, we questioned the role of mandatory operative exploration for all adult intussusceptions.
METHODS: This study is a retrospective review of all adults treated from 1983 to 2008 at a large tertiary referral center for intussusception.
RESULTS: One hundred ninety-six patients had intussusception over the 25-year study period. Computed tomography was obtained in 60% of patients. Neoplasms [malignant, (21%); benign, (24%)] were the commonest etiology; 30% cases were idiopathic. One hundred twenty (61%) patients underwent operative treatment for intussusception. Six of the 58 idiopathic or asymptomatic cases were operated on with negative findings in all. Palpable mass (OR 4.56, p < 0.035), obstructive symptoms (OR 9.13, p < 0.001) or obstruction (OR 9.67, p < 0.001), GI bleeding (OR 14.41, p < 0.001), and a lead point on computed tomography (OR 10.08, p < 0.001) were associated with the need for operation.
CONCLUSION: In the current era of computed tomography, idiopathic or asymptomatic intussusception is being seen more commonly; however, the majority of adult intussusceptions still have pathologic lead points. From our experience, all patients with palpable mass, obstructive symptoms or obstruction, gastrointestinal bleeding, or a lead point on computed tomography should undergo operative exploration.
J Gastrointest Surg. 2011 Oct;15(10):1699-705. doi: 10.1007/s11605-011...

Univariate analysis of predictors of malignant neoplasms

a:悪性腫瘍の予測因子に関する単変量解析(N=196)
b:手術の必要性に関する単変量解析(N=196)
c:病因の予測因子としてのCTでの先進部病変描出(N=88)
出典
imgimg
1: Adult intussusception in the last 25 years of modern imaging: is surgery still indicated?
著者: Onkendi EO, Grotz TE, Murray JA, Donohue JH.
雑誌名: J Gastrointest Surg. 2011 Oct;15(10):1699-705. doi: 10.1007/s11605-011-1609-4. Epub 2011 Jul 6.
Abstract/Text: BACKGROUND: Because most adult intussusceptions are reportedly due to malignancy, operative treatment is recommended. With current availability of computed tomography, we questioned the role of mandatory operative exploration for all adult intussusceptions.
METHODS: This study is a retrospective review of all adults treated from 1983 to 2008 at a large tertiary referral center for intussusception.
RESULTS: One hundred ninety-six patients had intussusception over the 25-year study period. Computed tomography was obtained in 60% of patients. Neoplasms [malignant, (21%); benign, (24%)] were the commonest etiology; 30% cases were idiopathic. One hundred twenty (61%) patients underwent operative treatment for intussusception. Six of the 58 idiopathic or asymptomatic cases were operated on with negative findings in all. Palpable mass (OR 4.56, p < 0.035), obstructive symptoms (OR 9.13, p < 0.001) or obstruction (OR 9.67, p < 0.001), GI bleeding (OR 14.41, p < 0.001), and a lead point on computed tomography (OR 10.08, p < 0.001) were associated with the need for operation.
CONCLUSION: In the current era of computed tomography, idiopathic or asymptomatic intussusception is being seen more commonly; however, the majority of adult intussusceptions still have pathologic lead points. From our experience, all patients with palpable mass, obstructive symptoms or obstruction, gastrointestinal bleeding, or a lead point on computed tomography should undergo operative exploration.
J Gastrointest Surg. 2011 Oct;15(10):1699-705. doi: 10.1007/s11605-011...

NISを用いた腸重積症手術患者の背景および転帰データ

出典
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1: Profiling adult intussusception patients: comparing colonic versus enteric intussusception.
著者: Alexander R, Traverso P, Bolorunduro OB, Ortega G, Chang D, Cornwell EE 3rd, Fullum TM.
雑誌名: Am J Surg. 2011 Oct;202(4):487-91. doi: 10.1016/j.amjsurg.2011.02.006.
Abstract/Text: BACKGROUND: Adult intussusception is a rare entity representing 1% of all adult bowel obstruction, hospital admissions secondary to intussusception historically has ranged between .003% and .02%. There is limited knowledge regarding enteric and colonic surgical intussusception patients and their associated conditions.
METHODS: A retrospective study was conducted using data from the National Inpatient Sample from 1998 to 2006. The inclusion criteria were surgical patients with intussusception.
RESULTS: A total of 1,178 cases of intussusception requiring surgery were isolated from the database. The mean patient age was 49.57 years, about 58% were females, 99.43% of this population was insured, and the overall mortality rate was 1.70%. Colonic resection was associated with greater mortality compared with the enteric resection group (P = .018).
CONCLUSIONS: This was a large study on surgical adult intussusception patients conducted in the United States. We show differences in demography, comorbidities, and potential causes between colonic and enteric intussusception.

Published by Elsevier Inc.
Am J Surg. 2011 Oct;202(4):487-91. doi: 10.1016/j.amjsurg.2011.02.006....

Location of intussusception

a:腸重積症の部位
b:治療の種類および腸切除率
c:関連所見
出典
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1: Intussusception in traditional pediatric, nontraditional pediatric, and adult patients.
著者: Cochran AA, Higgins GL 3rd, Strout TD.
雑誌名: Am J Emerg Med. 2011 Jun;29(5):523-7. doi: 10.1016/j.ajem.2009.11.023. Epub 2010 Apr 2.
Abstract/Text: STUDY OBJECTIVES: We sought to determine the rate of intussusception in 3 age groups (traditional pediatric-age [T], nontraditional pediatric-age [N], and adult-age [A]) and to compare group characteristics.
METHODS: We conducted a retrospective records review for patients discharged with diagnosis of intussusception between October 1999 and June 2008.
RESULTS: Ninety-five cases of intussusception were diagnosed as follows: 61 T (64%), 12 N (13%), and 22 A (23%). Bloody stool was more common in T patients (P = .016). Air contrast enema (36%) and ultrasound (33%) were the most common diagnostic tests in T, whereas computed tomography was most common in N (83%) and A (68%) patients. Bowel resection occurred more often in older (T) patients (P = .001). The most frequent causative pathologic conditions were adenitis (T), Peutz-Jeghers polyp (N), and carcinoma (A) and prior gastric bypass in 10 A patients.
CONCLUSIONS: The incidence of intussusception is substantially higher in nontraditional age groups than previously reported. Symptoms, management strategies, and causative pathologic conditions varied with age. All adults with intussusception require definitive diagnostic testing to determine the cause, given the concerning list of possibilities we observed.

Copyright © 2011 Elsevier Inc. All rights reserved.
Am J Emerg Med. 2011 Jun;29(5):523-7. doi: 10.1016/j.ajem.2009.11.023....

腸重積症の典型的画像所見:定義および鑑別診断

出典
imgimg
1: Intussusception in adults: what radiologists should know.
著者: Baleato-González S, Vilanova JC, García-Figueiras R, Juez IB, Martínez de Alegría A.
雑誌名: Emerg Radiol. 2012 Apr;19(2):89-101. doi: 10.1007/s10140-011-1006-z. Epub 2011 Dec 27.
Abstract/Text: Adult intussusception (AI) is a rare entity with an organic lesion within the intussusception in 70-90% of the cases. Intussusception is classified according to location, etiology, and to the presence or not of a lead point. We illustrate several causes of AI with a variety of radiological findings on plain film, ultrasonography, computed tomography, magnetic resonance, and endoscopy seen at our institution. Imaging plays a major role in their diagnosis and in determining the appropriate treatment.
Emerg Radiol. 2012 Apr;19(2):89-101. doi: 10.1007/s10140-011-1006-z. E...

S状結腸軸捻転治療アルゴリズム

出典
imgimg
1: Volvulus of the sigmoid colon.
著者: Raveenthiran V, Madiba TE, Atamanalp SS, De U.
雑誌名: Colorectal Dis. 2010 Jul;12(7 Online):e1-17. doi: 10.1111/j.1463-1318.2010.02262.x. Epub 2010 Mar 10.
Abstract/Text: AIMS: The current status of sigmoid volvulus (SV) was reviewed to assess trends in management and to assess the literature.
METHOD: The literature on SV was retrieved using PubMed, Embase, Scopus, Pakmedinet, African Journals online (AJOL), Indmed and Google scholar. These databases were searched for text words including 'sigmoid', 'colon' and 'volvulus'. Relevant nonindexed surgical journals published from endemic countries were also manually searched. We focused on original articles published within the last 10 years; but classical references prior to this period were also included. Seminal papers published in non-English languages were also included.
RESULTS: Sigmoid volvulus is a leading cause of acute colonic obstruction in South America, Africa, Eastern Europe and Asia. It is rare in developed countries such as USA, UK, Japan and Australia. Characteristic geographic variations in the incidence, clinical features, prognosis and comorbidity of SV justify recognition of endemic and sporadic subtypes. Controversy on aetiologic agents can be minimized by classifying them into 'predisposing' and 'precipitating' factors. Modern imaging systems, although more effective than plain radiographs, are yet to gain popularity. Emergency endoscopic reduction is the treatment of choice in uncomplicated patients. But it is only a temporizing procedure, and it should be followed in most cases by elective definitive surgery. Resection of the redundant sigmoid colon is the gold standard operation. The role of newer nonresective alternatives is yet to be ascertained. Although emergency resection with primary anastomosis (ERPA) has been controversial in the past, it is now increasingly accepted as a safe option with superior results. Management in elderly debilitated patients is extremely difficult. Paediatric SV significantly differs from that in adults. SV is frequently associated with neuropsychiatric diseases, diabetes mellitus and Chagas disease. The overall mortality in recent studies is < 5%.
CONCLUSION: There are almost no randomised controlled studies. According to the grading system of Oxford Center for Evidence Based Medicine (CEVM), available published evidence is at level 4. The recommendations resulting form this review are of 'C' grade.
Colorectal Dis. 2010 Jul;12(7 Online):e1-17. doi: 10.1111/j.1463-1318....

腸重積の腹部CT(target pattern)

内部に低吸収域と高吸収域が混在する同心円状の層状構造を持つ腫瘤陰影を認める。重積を横断面像として捉えるとtarget patternとして描出される。
出典
imgimg
1: Intussusception in adults: what radiologists should know.
著者: Baleato-González S, Vilanova JC, García-Figueiras R, Juez IB, Martínez de Alegría A.
雑誌名: Emerg Radiol. 2012 Apr;19(2):89-101. doi: 10.1007/s10140-011-1006-z. Epub 2011 Dec 27.
Abstract/Text: Adult intussusception (AI) is a rare entity with an organic lesion within the intussusception in 70-90% of the cases. Intussusception is classified according to location, etiology, and to the presence or not of a lead point. We illustrate several causes of AI with a variety of radiological findings on plain film, ultrasonography, computed tomography, magnetic resonance, and endoscopy seen at our institution. Imaging plays a major role in their diagnosis and in determining the appropriate treatment.
Emerg Radiol. 2012 Apr;19(2):89-101. doi: 10.1007/s10140-011-1006-z. E...