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保存的治療例:症例1

a:初診時。左大腿骨頭近位骨端核の硬化像を認める。
b:発症後10カ月。壊死期、装具療法継続中。
c:発症後1年9カ月。修復像が認められ装具を除去した。
d:最終調査時。発症後12年ではStulberg分類はclassⅡ、臨床的な異常を認めず経過良好である。
出典
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1: 著者提供

保存的治療例:症例2

a:初診時。左大腿骨頭近位骨端核の硬化像を認める。
B:発症後1年。壊死期、装具療法継続中であるが骨端核の圧潰が進んでいる。
c:発症後2年2カ月。修復像が認められ装具を除去した。
D:最終調査時。発症後4年2カ月経過時のものでStulberg分類はclassⅣ、臨床的には時々股関節痛、腰痛を認めるということで、治療成績は芳しくない。
出典
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1: 著者提供

手術的治療例:症例3

a:初診時。右大腿骨頭近位骨端核の壊死像を認め、亜脱臼も存在する。
B:術直後。転子間内反骨切り術
c:術後1年。骨切り部の骨癒合は完了している。骨端部は修復が進みすでに全荷重を許可している。
d:最終調査時。発症後2年1カ月(術後1年5カ月)経過時のものでStulberg分類はclassⅡ、軽度の大転子高位は認めるものの臨床的には異常なく経過良好である。
出典
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1: 著者提供

単純X線像における経時的変化と病期

A:硬化期
B:壊死期
C:修復期(分節期)
出典
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1: 著者提供

Catterall分類

a:GroupⅠ。骨端核前方のみの変化で陥没はない。
b:GroupⅡ。骨端核前方の大きな変化と陥没がある。
c:GroupⅢ。後方の一部を除き骨端核全体に変化と陥没がみられる。骨幹端部の変化が広範で頚部幅の拡大もみられる。
d:GroupⅣ。骨端核全体が陥没して骨頭の扁平化が著明。骨幹端部の変化も広範にみられる。
 
参考文献:Catterall A: The natural history of Perthes’ disease. J Bone Joint Surg 53-B: 37-53, 1971.

Head at risk sign

Gage’s sign:骨幹端外前方にみられるV sign
 
参考文献:
Catterall A: The natural history of Perthes’ disease. J Bone Joint Surg 53-B: 37-53, 1971.

Herring分類

a:Group A,B,C
b:B/C境界型
①外側部の骨性支柱の高さは50%以上保たれているが、非常に細い場合(2~3mm)。
②外側でうっすらと石灰化している部分も合わせると何とか外側部骨性支柱の高さは50%以上あるもの。
③外側部骨性支柱の高さはちょうど50%であるが、中央部に対しては低くなっているケース。
出典
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1: Legg-Calve-Perthes disease. Part I: Classification of radiographs with use of the modified lateral pillar and Stulberg classifications.
著者: John A Herring, Hui Taek Kim, Richard Browne
雑誌名: J Bone Joint Surg Am. 2004 Oct;86-A(10):2103-20.
Abstract/Text: BACKGROUND: Accurate and reliable radiographic classifications of the relative severity and outcome of Legg-Calve-Perthes disease are essential in the study of that disease. As part of a prospective multicenter study, we sought to define more clearly the lateral pillar classification of severity and the Stulberg classification of outcome; we sought especially to define the borderlines between classification groups.
METHODS: We performed interobserver and intraobserver trials of the lateral pillar and Stulberg classifications using sets of twenty radiographs chosen from a prospective study of 345 hips. To establish reliable definitions of the lateral pillar classification, we added a new, intermediate group termed the B/C border group, which includes femoral heads with a thin or poorly ossified lateral pillar and those with a loss of exactly 50% of the original height of the lateral pillar. The resulting classification consists of four groups: A, B, B/C border, and C. In our application of the classification system of Stulberg et al., we defined a class-II femoral head as round and fitting within 2 mm of a circle on both anteroposterior and frog-leg lateral radiographs. We defined a Stulberg class-III femoral head as out of round by more than 2 mm on either view and a Stulberg class-IV femoral head as one with at least 1 cm of flattening of the weight-bearing articular surface. To assess interobserver and intraobserver agreement, we performed two trials of each classification with six orthopaedic surgeons reviewing twenty radiographs or pairs of radiographs.
RESULTS: In the first trial of the lateral pillar classification, there was 81% agreement per radiograph and the average weighted kappa was 0.71. In the second trial, there was 85% agreement per radiograph and the weighted kappa averaged 0.79. Intraobserver reliability testing showed a 77% match between Trials 1 and 2, an average weighted kappa of 0.81, and an average generalizability coefficient of 0.91. In Trial 1 of the Stulberg classification, there was 91% agreement per radiograph and an average weighted kappa of 0.82. In Trial 2, there was 92% agreement per radiograph and an average weighted kappa of 0.82. Intraobserver reliability testing showed an 89% match between Trials 1 and 2, an average weighted kappa value of 0.88, and an average generalizability coefficient of 0.92.
CONCLUSIONS: The interobserver and intraobserver trials of these classifications produced kappa values and generalizability coefficients in the excellent range. The modified lateral pillar classification and the redefined Stulberg classification are sufficiently reliable and accurate for use in studies of Legg-Calve-Perthes disease.
J Bone Joint Surg Am. 2004 Oct;86-A(10):2103-20.

ペルテス病のMRI画像

a:T1強調画像
b:T2強調画像
出典
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1: 著者提供

Stulberg分類

a:ClassI
b:ClassⅡ
c:ClassⅢ
d:ClassIV
e:ClassV
出典
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1: The natural history of Legg-Calvé-Perthes disease.
著者: S D Stulberg, D R Cooperman, R Wallensten
雑誌名: J Bone Joint Surg Am. 1981 Sep;63(7):1095-108.
Abstract/Text: Two groups of patients who had Legg-Calvé-Perthes disease were studied. The first group of patients consisted of eighty-eight patients (ninety-nine affected hips) followed in three hospitals for an average of forty years. The second group consisted of sixty-eight patients (seventy-two affected hips), all of whose radiographs from the onset of disease to maturity were available and all of whom had been treated in one hospital. The patients in this second group were followed for an average of thirty years. Each hip in both study groups could be placed into one of five classes of deformity based on its radiographic appearance at maturity. Each class showed a characteristic pattern of involvement during the active stages of the disease and had a specific long-term clinical and radiographic course. The clinical and radiographic course of an involved hip subsequent to childhood was related to the type of congruency that existed between the femoral head and acetabulum. Three types of congruency were recognized: (1) spherical congruency (Class-I and II hips) - in hips in this category arthritis does not develop; (2) aspherical congruency (Class-III and IV hips) - mild to moderate arthritis develops in late adulthood in these hips; and (3) aspherical incongruency (Class-V hips) - severe arthritis develops before the age of fifty years in these hips.
J Bone Joint Surg Am. 1981 Sep;63(7):1095-108.

装具の種類

a:Toronto装具
b:Tachdjian装具
c:Newington装具
d:Atlanta装具
出典
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1: Tachdjian's Pediatric Orthopaedics, Vol.1, 3rded,Saunders, Philadelphia.,2002;695-698

ペルテス病の診療アルゴリズム

出典
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1: 著者提供