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著者: Rosalyn E O'Loughlin, Karen Edmond, Punam Mangtani, Adam L Cohen, Sharmila Shetty, Rana Hajjeh, Kim Mulholland
雑誌名: Vaccine. 2010 Aug 31;28(38):6128-36. doi: 10.1016/j.vaccine.2010.06.107. Epub 2010 Jul 23.
Abstract/Text
The use of the highly effective Haemophilus influenzae type b (Hib) conjugate vaccine has increased globally. We review the benefits and limitations of studies measuring Hib vaccine effectiveness (VE). We critically examine the case-control approach by assessing the similarities and differences in methodology and findings and discuss the need for future Hib VE studies. In the absence of good surveillance data, vaccine effectiveness studies can play an important role, particularly with the increasing use of pneumococcal vaccine that has not been well tested under field conditions in less developed countries. However, the effectiveness of Hib vaccine has been well documented so the need for future VE Hib studies is minimal.
(c) 2010 Elsevier Ltd. All rights reserved.
PMID 20655402 Vaccine. 2010 Aug 31;28(38):6128-36. doi: 10.1016/j.vaccine.2010.06.107. Epub 2010 Jul 23.
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