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著者: Takayuki Matsumoto, Shotaro Nakamura, Motohiro Esaki, Shinnichiro Yada, Hideki Koga, Takashi Yao, Mitsuo Iida
雑誌名: Dig Dis Sci. 2006 Aug;51(8):1357-63. doi: 10.1007/s10620-006-9080-x. Epub 2006 Jul 26.
Abstract/Text
Chronic nonspecific multiple ulcers of the small intestine (CNSU) and nonsteroidal anti-inflammatory drug-induced enteropathy (NSAID-enteropathy) share common clinicopathologic features characterized by histologically nonspecific ulcers and persistent blood loss. The aim was to compare enteroscopic findings between CNSU and NSAID-enteropathy. Four patients with CNSU and five patients with NSAID-enteropathy were examined by enteroscopies. The site of involvement was heterogeneous in NSAID-enteropathy, while the ileum was the predominant site in CNSU. Three patients with NSAID-enteropathy and all four patients with CNSU had concentric stenosis. Circular ulcers were found in all five patients with NSAID-enteropathy and in three patients with CNSU. Active ulcer was seen in only two patients with NSAID-enteropathy. In contrast, all four patients with CNSU had active ulcer. These findings suggest that in patients with persistent GI bleeding and enteroscopically active small intestinal ulcers, CNSU, as well as NSAID-enteropathy, should be considered.
PMID 16868823 Dig Dis Sci. 2006 Aug;51(8):1357-63. doi: 10.1007/s10620-006-9080-x. Epub 2006 Jul 26.
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