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著者: R J Norman, S Mahabeer, S Masters
雑誌名: Fertil Steril. 1995 Jan;63(1):58-62.
Abstract/Text
OBJECTIVE: To examine different patterns of glucose and insulin secretion in women (of both Indian and white ethnic backgrounds) with polycystic ovary syndrome (PCOS).
DESIGN: A 75-g oral glucose tolerance test was performed in 11 subjects from each group.
SETTING: Reproductive Medicine and Gynecological Clinics from The Queen Elizabeth Hospital, Woodville, South Australia, and King Edward the VIIIth Hospital, Durban, South Africa.
PATIENTS: Couples were grouped as follows: Indian nonobese and obese PCOS, Indian nonobese and obese reference subjects, white nonobese and obese PCOS, white nonobese and obese reference subjects.
MAIN OUTCOME MEASURE: Insulin and glucose in plasma after oral glucose testing.
RESULTS: Indian PCOS and nonobese reference subjects had higher insulin responses than whites. The ethnic difference was less pronounced in obese women. There were no ethnic differences in glucose response.
CONCLUSION: This study demonstrates that the ethnic background of subjects with PCOS needs to be considered in studies on the metabolic parameters in this condition.
PMID 7805925 Fertil Steril. 1995 Jan;63(1):58-62.
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