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著者: Dennis L Stevens, Amy E Bryant, Ellie Jc Goldstein
雑誌名: Infect Dis Clin North Am. 2021 Mar;35(1):135-155. doi: 10.1016/j.idc.2020.10.004. Epub 2020 Dec 7.
Abstract/Text
Necrotizing soft tissue infections occur after traumatic injuries, minor skin lesions, nonpenetrating injuries, natural childbirth, and in postsurgical and immunocompromised patients. Infections can be severe, rapidly progressive, and life threatening. Survivors often endure multiple surgeries and prolonged hospitalization and rehabilitation. Despite subtle nuances that may distinguish one entity from another, clinical approaches to diagnosis and treatment are highly similar. This review describes the clinical and laboratory features of necrotizing soft tissue infections and addresses recommended diagnostic and treatment modalities. It discusses the impact of delays in surgical debridement, antibiotic use, and resuscitation on mortality, and summarizes key pathogenic mechanisms.
Copyright © 2020 Elsevier Inc. All rights reserved.
PMID 33303335 Infect Dis Clin North Am. 2021 Mar;35(1):135-155. doi: 10.1016/j.idc.2020.10.004. Epub 2020 Dec 7.
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