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img  2:  Neuropathological basis of nonmotor manifestations of Parkinson's disease.
 
著者: Adler CH, Beach TG.
雑誌名: Mov Disord. 2016 Aug;31(8):1114-9. doi: 10.1002/mds.26605. Epub 2016 Mar 31.
Abstract/Text Nonmotor manifestations of Parkinson's disease (PD) can begin well before motor PD begins. It is now clear, from clinical and autopsy studies, that there is significant Lewy-type α-synucleinopathy present outside the nigro-striatal pathway and that this may underlie these nonmotor manifestations. This review discusses neuropathological findings that may underlie nonmotor symptoms that either predate motor findings or occur as the disease progresses. © 2016 International Parkinson and Movement Disorder Society.

© 2016 International Parkinson and Movement Disorder Society.
PMID 27030013  Mov Disord. 2016 Aug;31(8):1114-9. doi: 10.1002/mds.26605. Epub 2016 Mar 31.

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