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img  1:  Group A streptococcal infections in children.
 
著者: Andrew C Steer, Margaret H Danchin, Jonathan R Carapetis
雑誌名: J Paediatr Child Health. 2007 Apr;43(4):203-13. doi: 10.1111/j.1440-1754.2007.01051.x.
Abstract/Text The group A streptococcus causes the widest range of disease in humans of all bacterial pathogens. Group A streptococcal diseases are more common in children than adults with diseases ranging from pharyngitis and impetigo to invasive infections and the post-streptococcal sequelae--acute rheumatic fever and acute post-streptococcal glomerulonephritis. The global burden of severe group A streptococcal disease is concentrated largely in developing countries and Indigenous populations such as Aboriginal Australians. Control of group A streptococcal disease is poor in these settings and the need for a vaccine has been argued. With an ever-increasing understanding of the group A streptococcus at a molecular level, new and sophisticated vaccines are currently in human trials and the next decade holds exciting prospects for curbing group A streptococcal diseases.

PMID 17444820  J Paediatr Child Health. 2007 Apr;43(4):203-13. doi: 10.1111/j.1440-1754.2007.01051.x.
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