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著者: Takafumi Koyama, Hiroyuki Yamamoto, Manabu Matsumoto, Jun Isogai, Tadashi Isomura, Shinji Tanaka
雑誌名: Front Cardiovasc Med. 2020;7:589212. doi: 10.3389/fcvm.2020.589212. Epub 2020 Oct 29.
Abstract/Text
Löffler's endocarditis (cardiac involvement in hypereosinophilic syndrome) is rare yet life-threatening if left untreated. We describe a case of hypereosinophilic syndrome presenting as a cardiac mass with an abnormal electrocardiogram. Diagnostic studies of the cardiac mass strongly suggested a malignant cardiac tumor invading the papillary muscle. Thus, excision of the cardiac mass and endomyocardial resection with mitral valve replacement were successfully performed. Pathology revealed various stages of thrombosis and irreversible myocardial damage caused by eosinophilic infiltration with no malignancy, leading to the correct diagnosis of late-stage Löffler's endocarditis. The subsequent combination of anticoagulation and corticosteroids was effective with a favorable outcome. This case highlights pitfalls in multimodality imaging of cardiac thrombus and the clinical significance of considering Löffler's endocarditis in the diagnostic work-up of a cardiac mass.
Copyright © 2020 Koyama, Yamamoto, Matsumoto, Isogai, Isomura and Tanaka.
PMID 33195478 Front Cardiovasc Med. 2020;7:589212. doi: 10.3389/fcvm.2020.589212. Epub 2020 Oct 29.
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