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著者: K Maeda, T Suzuki, Y Ooyama, K Nakakuki, M Yamashiro, N Okada, T Amagasa
雑誌名: Int J Oral Maxillofac Surg. 2010 May;39(5):486-92. doi: 10.1016/j.ijom.2009.11.001. Epub 2009 Dec 5.
Abstract/Text
To determine whether the measurement of staining with 3% Lugol's solution provided efficient criteria for determining the area of resection for oral carcinomas and oral potentially malignant disorders, the authors analyzed the color of unstained lesions (USLs) in relation to histopathological findings. After vital iodine staining, USLs were seen in 48 of 54 patients (88.9%). A significant difference was seen in the value of lightness between stained lesions (SLs) and USLs for patients with moderate and severe epithelial dysplasia (P<0.001). The deviation between the macroscopically observable and the histopathological boundaries was -0.65+/-1.26 mm (range: -4.36 to 1.52). Color charts prepared on the basis of values for lightness and hue reproduced the macroscopic color differences in USLs, suggesting that it may become possible to diagnose USLs histologically on the basis of the measured color values and use of color charts to help determine the resection area in surgery.
Copyright 2009 International Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.
PMID 19963354 Int J Oral Maxillofac Surg. 2010 May;39(5):486-92. doi: 10.1016/j.ijom.2009.11.001. Epub 2009 Dec 5.
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