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著者: M Umeda, H Komatsubara, Y Ojima, T Minamikawa, Y Shibuya, S Yokoo, J Ishii, T Komori
雑誌名: Int J Oral Maxillofac Surg. 2005 Oct;34(7):739-44. doi: 10.1016/j.ijom.2005.02.015.
Abstract/Text
The treatment method for early stage tongue cancer is still controversial in Japan. The aim of this study is to compare the prognosis for patients with early tongue cancer treated with brachytherapy and surgery. A retrospective study was conducted to compare the efficacy of low-dose-rate brachytherapy (LDR), high-dose-rate brachytherapy (HDR), and surgery for early tongue cancer. A total of 180 patients with stage I-II tongue cancer were divided into three treatment groups: LDR (78), HDR (26), and surgery (71). Local recurrence was seen in thirteen patients (17%) of the LDR, nine (35%) of the HDR, and four (6%) of the surgery group. After salvage therapy, final local cure was obtained for 71 patients (91%) of the LDR, 22 (85%) of the HDR, and 71 (100%) of the surgery group. Neck failure was recorded for eight patients in the LDR, six in the HDR, and three in the surgery group. The respective 5-year overall survival rates for the LDR, HDR and surgery groups were 84.0%, 72.9%, 95.4% for stage I, and 72.2%, 51.5%, 93.8% for stage II. These findings show that surgery is the optimal treatment method for patients with stage I-II tongue cancer.
PMID 15921890 Int J Oral Maxillofac Surg. 2005 Oct;34(7):739-44. doi: 10.1016/j.ijom.2005.02.015.
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