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著者: Osamu Ishihara, Akira Kuwahara, Hidekazu Saitoh
雑誌名: Fertil Steril. 2011 May;95(6):1966-9. doi: 10.1016/j.fertnstert.2011.02.015. Epub 2011 Mar 5.
Abstract/Text
OBJECTIVE: To evaluate the effect of frozen-thawed blastocyst transfer on ectopic pregnancy (EP) rate.
DESIGN: Retrospective analysis.
SETTING: Japanese registry of assisted reproductive medicine.
PATIENT(S): Women who were registered during 2008.
INTERVENTION(S): None.
MAIN OUTCOME MEASURE(S): Rates of live birth, EP, and spontaneous abortion in single blastocyst and cleavage-stage ET cycles in both fresh and frozen-thawed were determined.
RESULT(S): In the frozen-thawed single blastocyst transfer cycles, 84 EPs of 10,312 clinical pregnancies (0.81%) were reported. There were 25 EPs of 1,361 clinical pregnancies (1.8%) in fresh IVF single blastocyst transfer cycles and 19 of 1,352 (1.4%) in fresh intracytoplasmic sperm injection single blastocyst transfer cycles. The rate of EPs after frozen-thawed single blastocyst transfers varied between 0.56% and 0.97% after stratification by age group.
CONCLUSION(S): Frozen-thawed blastocyst transfers have reduced EP rates significantly compared with fresh blastocyst transfers.
Copyright © 2011 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.
PMID 21377154 Fertil Steril. 2011 May;95(6):1966-9. doi: 10.1016/j.fertnstert.2011.02.015. Epub 2011 Mar 5.
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