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著者: Angela Vivanti, Keren Harvey, Susan Ash, Diana Battistutta
雑誌名: Arch Gerontol Geriatr. 2008 Nov-Dec;47(3):340-55. doi: 10.1016/j.archger.2007.08.016. Epub 2007 Nov 9.
Abstract/Text
Due to an absence of published primary data, this study explores dehydration prevalence and the change in physiological parameters frequently used to assess dehydration (fluid deficit) in older hospitalized people, as no standard measurement method exists. This observational longitudinal cohort study recruited 43 people aged 60 years or over, voluntarily admitted to a tertiary teaching hospital's Geriatric and Rehabilitation Unit (GARU). Over 40 clinical, hematological and urinary biochemical parameters employed by medical officers during dehydration assessment, identified through literature, interviews and focus group were investigated. Short-term weight changes, intra- and inter-rater repeatability of dehydration assessments were completed to assess validation and precision of the clinician's clinical dehydration assessment. Systolic blood pressure drop on standing, sternal skin turgor, tongue dryness and body mass index (BMI) were associated with hydration status; demonstrated clinically meaningful differences between groups. BMI negatively confounded the association between dehydration and systolic blood pressure drop on standing. Physical, rather than biochemical, parameters more often identified mild dehydration. The findings challenge common expectations of hematological and physiological measurement changes occurring in older people clinically assessed as dehydrated and emphasize the need to adjust for potential confounders during exploration of the associations of clinical parameters with dehydration status.
PMID 17996966 Arch Gerontol Geriatr. 2008 Nov-Dec;47(3):340-55. doi: 10.1016/j.archger.2007.08.016. Epub 2007 Nov 9.
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